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Phentermine and topiramate, also commonly known as phentermine hydrochloride-topiramate, is a popular weight-loss drug known by the brand named Qsymia.
They are combined to provide additional benefits for weight loss and the suppression of appetite.
Phentermine topiramate, when sold under the brand name Qsymia, is only available for sale through prescription because of its classification as a Schedule IV controlled substance.
Phentermine has long been used in weight loss and obesity treatment programs.
The combination is commonly prescribed for individuals struggling with chronic weight management in addition to diet and an increase in physical activity. Click here to buy Phentermine online.
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Table of Contents
When combined with diet and exercise, it has shown an ability to enhance weight loss.
The specific action or chemical reactions involving phentermine are currently unknown, but it is strongly believed that it plays a role in the release of catecholamine from the hypothalamus.
This action produces decreased appetite, which in turn leads to a decreased intake of calories.
To date, the actual function of topiramate when combined with phen is unknown, at least in regard to weight management. However, topiramate is believed to promote a sense of fullness or satiety in individuals due to its effects on neurotransmitters and enzyme functions.
When used according to directions and guidance provided by a physician or bariatric specialist, the combination of phentermine and topiramate reviews consider it relatively safe.
Of course, safety and effectiveness may depend on a number of factors including not only age and overall health, but the ability of the patient to adhere to dietary requirements, exercise levels, and changes in eating behaviors or disorders.
Phentermine hydrochloride topiramate is available in capsules of various milligram strengths:
Your doctor will determine dosage, although this combination of drugs may be limited to individuals with a starting body mass index or BMI of 30 kg per square meter or greater, classified as obese, or 27 kg per square meter or greater, classified as overweight along with associated or linked to a least one related comorbidity.
Comorbidity factors of obesity include Type 2 diabetes, dyslipidemia, and hypertension, among others.
The dosage recommendations for adults typically begins with a 3.75 mg phentermine/23 mg topiramate extended-release tablet or capsule for approximately 14 days, taken in the morning.
Phentermine may cause insomnia in some, so it is recommended to be taken at least 12 to 14 hours before bedtime to avoid this side effect.
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Depending on results, milligram dosage may be increased by your doctor, up to 12 weeks of treatment, at which point your doctor will evaluate your weight-loss efforts.
In most cases, if patients haven’t lost a minimum of 3% of their initial bodyweight within the initial 12-week treatment plan, the doctor may decide to either discontinue the medication or increase the dosage to 11.25 mg phentermine/69 mg topiramate for another 14 days.
Constant evaluation and monitoring is essential when taking weight-loss drugs. Because of the belief that phentermine has addictive qualities and potential for abuse, misuse and withdrawal, it is classified as a controlled substance.
In most cases, it is designed for short-term use, as efficacy can fade over time.
However, it should be noted, depending on circumstances, that longer-term use as well as combinations of a phentermine and topiramate dosage may be recommended by bariatric specialists on a case-by-case basis.
Any drug has the potential to cause side effects, and even over-the-counter and herbal remedies like Phentramin D and supplements often involve interactions, side effects, and contraindications against use.
Phentermine and topiramate for weight loss may interact with certain drugs including anticholinergics, amitriptyline, and carbamazepine.
It may also negatively interact with central nervous system depressants including sleep medications. Individuals taking antidepressants should also use caution.
The same applies to anti-dietetic medications, oral contraceptives, and in conjunction with other weight-loss drugs, even herbal weight-loss supplements.
Scientific research regarding interactions with other herbs and weight-loss supplements hasn’t been studied, so it is suggested that individuals avoid use of them altogether.
Alcohol is also discouraged, because when combined with these weight loss drugs, it may increase the depressant defects to the central nervous system.
In order to avoid unpleasant side effects, interactions, or danger when using, discuss and understand its use with your doctor.
Tell your doctor every medication you’re taking, including prescription, over-the-counter, and herbal supplement to ensure that it the effect of phentermine and topiramate combination weight loss drugs provide the greatest efficacy while still maintaining safety.